This new version of the 1958 sci-fi hit isn’t just a remake but a complete reimagining, with director David Cronenberg mixing in his own sensibilities about organic life and its startling mutability. Teletransporter inventor Seth Brundle (Jeff Goldblum) inadvertently mixes his genes with a house fly’s when he decides to use himself as test subject. His future as a human being, including his romance with science writer Veronica (Geena Davis), changes forever as he begins a slow slide into a gooey half-man/half-insect, complete with superpowers and messianic delusions of grandeur. Chris Walas and Stephen Dupuis won Oscars in 1987 for Best Make-Up.